## Background: Even the high incidence of clinically diagnosed prostate cancer is exceeded by the frequency of tumors detected at autopsy. however, there is some debate concerning the malignant potential of these so-called "latent prostate cancers." in this study, prostate cancers detected at autop
Chromosomal changes during development and progression of prostate adenocarcinomas
✍ Scribed by Zitzelsberger, H; Engert, D; Walch, A; Kulka, U; Aubele, M; Höfler, H; Bauchinger, M; Werner, M
- Book ID
- 111724419
- Publisher
- Nature Publishing Group
- Year
- 2001
- Tongue
- English
- Weight
- 179 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0007-0920
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract In the normal prostate epithelium, androgen receptor (AR) negative basal epithelial cells adhere to the substratum, while AR expressing secretory cells lose substratum adhesion. In contrast, prostate cancer cells both express AR and adhere to a tumor basement membrane. In this review, w
In a recent allelotypic analysis of differentiated adenocarcinoma of the stomach, loss of heterozygosity (LOH) was found frequently on chromosomes 2q, 4p, 5q, 6p, 7q, 11q, 14q, 17p, 18q, and 21q. To clarify the sequence of these chromosomal losses during gastric carcinogenesis, microsatellite analys