6/155), high white cell number (13/155) (red cell unit) or low thrombocyte number (14/125) (thrombocyte unit). Summary: Donors with low hemoglobin levels have to be excluded from the blood donation service for 3 months. So, in theory haemoglobin concentration of all total blood units is suitable for
Chromosomal abnormalities in Philadelphia chromosome negative metaphases appearing during imatinib mesylate therapy in patients with newly diagnosed chronic myeloid leukemia in chronic phase
β Scribed by Jabbour, E.; Kantarjian, H. M.; Abruzzo, L. V.; O'Brien, S.; Garcia-Manero, G.; Verstovsek, S.; Shan, J.; Rios, M. B.; Cortes, J.
- Book ID
- 121733711
- Publisher
- American Society of Hematology
- Year
- 2007
- Tongue
- English
- Weight
- 117 KB
- Volume
- 110
- Category
- Article
- ISSN
- 0006-4971
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## Abstract ## BACKGROUND Anecdotal cases of chromosomal abnormalities in Philadelphia chromosome (Ph)βnegative metaphases have been reported in patients with chronic myelogenous leukemia (CML) in the chronic phase during treatment with interferon and, more recently, with imatinib. This phenomenon
## Abstract ## BACKGROUND The International Randomized study of Interferonβalpha plus cytarabine (IFNβΞ± plus araβC) versus STI571 (imatinib mesylate) [IRIS trial] in patients with newly diagnosed Philadelphia chromosome (Ph)βpositive, chronicβphase chronic myelogenous leukemia (CML) has not shown