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Chromosomal abnormalities in Philadelphia chromosome negative metaphases appearing during imatinib mesylate therapy in patients with newly diagnosed chronic myeloid leukemia in chronic phase

✍ Scribed by Jabbour, E.; Kantarjian, H. M.; Abruzzo, L. V.; O'Brien, S.; Garcia-Manero, G.; Verstovsek, S.; Shan, J.; Rios, M. B.; Cortes, J.


Book ID
121733711
Publisher
American Society of Hematology
Year
2007
Tongue
English
Weight
117 KB
Volume
110
Category
Article
ISSN
0006-4971

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## Abstract ## BACKGROUND The International Randomized study of Interferon‐alpha plus cytarabine (IFN‐α plus ara‐C) versus STI571 (imatinib mesylate) [IRIS trial] in patients with newly diagnosed Philadelphia chromosome (Ph)‐positive, chronic‐phase chronic myelogenous leukemia (CML) has not shown