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Chromatographic behavior of oxygenated derivatives of cholesterol

✍ Scribed by Hui Shan; Jihai Pang; Shengrong Li; Tony B Chiang; William K Wilson; George J Schroepfer Jr.


Book ID
117213583
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
244 KB
Volume
68
Category
Article
ISSN
0039-128X

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Sterol synthesis in liver in vivo is regulated at the site of the reaction catalyzed by 3-hydroxy-3-methylglutaryl-CoA reductase through a feedback system thought to involve either cholesterol or one or more of the products of its metabolism. Cholesterol feeding results in repression of the synthesi