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Chromatographic analysis of allosteric effects between ibuprofen and benzodiazepines on human serum albumin

✍ Scribed by Jianzhong Chen; Ilona Fitos; David S. Hage


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
309 KB
Volume
18
Category
Article
ISSN
0899-0042

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A chromatographic method was employed to study the kinetics of human serum albumin (HSA) adsorbed on immobilized monoclonal antibodies. The antibodies of various specificities were covalently bound to a high-performance liquid chromatography (HPLC) silica support. For very low desorption rates, succ