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Chromatin structure at the 3′-boundary of the human β-globin locus control region hypersensitive site-2

✍ Scribed by AeRi Kim; Vincent Murray


Book ID
117755721
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
287 KB
Volume
33
Category
Article
ISSN
1357-2725

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## Abstract LCR, a genetic regulatory element, was examined in β‐thalassemia patients who do not show any mutation in the β‐globin genes. We sequenced LCR‐HS2, HS3, and HS4 in samples from 16 such patients from the Indian population and found only one SNP A‐G in the inverted repeat in HS4. A signif