## Abstract Embryonic stem cells have an unlimited potential for selfโrenewal yet are pluripotent, capable of differentiating into three different germ layers and ultimately into multiple cell lineages. Key pluripotency specific factors maintain an undifferentiated ES cell phenotype while lineage s
Chromatin remodeling during mouse and human embryonic stem cell differentiation
โ Scribed by Jonathan L. Golob; Sharon L. Paige; Veronica Muskheli; Lil Pabon; Charles E. Murry
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 564 KB
- Volume
- 237
- Category
- Article
- ISSN
- 1058-8388
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract Temporal analysis in gene expression during differentiation of neural stem cells (NSCs) was performed by using inโhouse microarrays composed of 10,368 genes. The changes in mRNA level were measured during differentiation day 1, 2, 3, 6, 12, and 15. Out of 10,368 genes analyzed, 259 gene
A retroviral gene trap vector (U3Tkneo) that selects for integrations in or near expressed 5ะ exons has been used to identify genes that are repressed during hematopoietic differentiation of mouse totipotent embryonic stem cells. The vector contains coding sequences for an HSV-thymidine kinase/neomy
## Abstract During embryogenesis, the formation of blood vessels proceeds by both vasculogenesis and angiogenesis. Both processes appear to be finely regulated. To date, factors and genes involved in the negative regulation of embryonic vasculogenesis remain largely unknown. Angiostatin is a proteo
## Abstract Epigenetic marks are important factors regulating the pluripotency and differentiation of human embryonic stem cells (hESCs). In this study, we analyzed H3K9 acetylation, an epigenetic mark associated with transcriptionally active chromatin, during endodermโlike differentiation of hESCs
## Abstract Mechanical forces have been reported to induce proliferation and/or differentiation in many cell types, but the role of mechanotransduction during embryonic stem cell fate decisions is unknown. To ascertain the role of mechanical strain in human embryonic stem cell (hESC) differentiatio