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Chromatin Challenges during DNA Replication and Repair

✍ Scribed by Anja Groth; Walter Rocha; Alain Verreault; Geneviève Almouzni

Book ID
116353390
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
730 KB
Volume
128
Category
Article
ISSN
0092-8674

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During DNA replication, transcription and DNA repair in eukaryotes, the cellular machineries performing these tasks need to gain access to the DNA that is packaged into chromatin in the nucleus. Chromatin is a dynamic structure that modulates the access of regulatory factors to the genetic material.