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Chromatin: CENP-B-mediated genome-wide surveillance

โœ Scribed by Skipper, Magdalena

Book ID
109952723
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
204 KB
Volume
9
Category
Article
ISSN
1471-0056

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We report the application of single-molecule-based sequencing technology for high-throughput profiling of histone modifications in mammalian cells. By obtaining over four billion bases of sequence from chromatin immunoprecipitated DNA, we generated genome-wide chromatin-state maps of mouse embryonic