Chondroid lipoma is characterized by t(11;16)(q13;p12–13)
✍ Scribed by Florence Ballaux; Maria Debiec-Rychter; Ivo Wever; Raf Sciot
- Book ID
- 106117032
- Publisher
- Springer
- Year
- 2004
- Tongue
- English
- Weight
- 201 KB
- Volume
- 444
- Category
- Article
- ISSN
- 1432-2307
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Several cytogenetic subgroups with characteristic lesions involving chromosomal regions 12q14-15, 6p21.3, or 13q12 can be distinguished in lipomas. Rearrangements of the HMGIC gene have been described in cases with 12q14-15 abnormalities, whereas HMGIY has been shown to be the target gene of 6p21.3
Fourteen cases of an atypical myeloproliferative disorder associated with consistent translocations involving 8p11-12 have previously been described. A t(8;13)(p11;q11-12) was the most common, but variant t(8;9)(p11-12;q32-34) and t(6;8)(q27;p12) were also reported. Here we have used a series of yea