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Cholinesterase evaluation in the prenatal diagnosis of open neural tube defects

✍ Scribed by Rosario Troccoli; Stefano Biagioni; Francesco Stella; Antonio Pachì; Michele Ermini; Marina Toschi; Gianfranco Scarsella; Mauro Giorgi


Publisher
Springer
Year
1985
Tongue
English
Weight
533 KB
Volume
15
Category
Article
ISSN
0940-5437

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Amniotic fluid cholinesterase of valproa
✍ Mohamed M. A. Elmazar; Richard Vogel; Horst Spielmann 📂 Article 📅 1988 🏛 Springer-Verlag 🌐 English ⚖ 321 KB

After a single administration of the antiepileptic drug valproic acid (VPA; i.p.:600 mg/kg) on day 8 of gestation in the mouse embryotoxicity and amniotic fluid (AF) cholinesterase (ChE) were evaluated on day 16 of gestation. VPA treatment induced an increase in embryolethality, neural tube defects