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Cholinergic stimulation of the nucleus basalis of Meynert and reticular thalamic nucleus affects spike-and-wave discharges in WAG/Rij rats

✍ Scribed by Rustam K. Berdiev; Gilles van Luijtelaar


Book ID
116771617
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
680 KB
Volume
463
Category
Article
ISSN
0304-3940

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In the WAG/Rij rat, a model for human absence epilepsy, spike-wave discharges (SWD) and absence epileptic behavior develop after the age of 3 months. The rostral part of the reticular thalamic nucleus (rRTN) is involved in SWD. Ca(2+) channels play a central role in the initiation and maintenance of