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Cholinergic regulation of VIP gene expression in human neuroblastoma cells

✍ Scribed by Bo Kristensen; Birgitte Georg; Jan Fahrenkrug


Book ID
114003201
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
1020 KB
Volume
775
Category
Article
ISSN
0006-8993

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## Abstract The CD44 adhesion receptor is silenced in highly malignant neuroblastomas (NBs) with __MYCN__ amplification. Because its functional expression is associated with decreased tumorigenic properties, __CD44__ behaves as a tumor suppressor gene in NB and other cancers. Given that the precise