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Cholesterol oxidation products and fibrogenesis

โœ Scribed by Gabriella Leonarduzzi; Alex Sevanian; Giuseppe Poli

Book ID
112010474
Publisher
IOS Press
Year
2001
Tongue
English
Weight
29 KB
Volume
15
Category
Article
ISSN
0951-6433

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4-Hydroxynonenal (HNE) is by far the most investigated aldehydic end-product of oxidative breakdown of membrane n-6 polyunsaturated fatty acids. Its potential involvement in the pathogenesis of atherosclerosis has been corroborated by its consistent detection in both oxidized LDL and fibrotic plaque