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Cholesterol-Lowering Therapy: Evaluation of Clinical Trial Evidence

✍ Scribed by Scott M. Grundy (Editor)


Publisher
CRC Press
Year
1999
Leaves
348
Edition
1
Category
Library

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✦ Synopsis


Reveals important new results from clinical trials conducted in Scandinavia, Scotland, Australia, Canada, and the United States.

This timely reference reviews the vast body of clinical trial evidence supporting the once controversial view that high levels of serum cholesterol are a major risk factor in coronary heart disease (CHD). The studies p

✦ Table of Contents


Cholesterol-Lowering Clinical Trials: A Historical Perspective

Scott M. Grundy

Scandinavian Simvastatin Survival Study (4S)

Terje R. Pedersen

The Cholesterol and Recurrent Events Trial (CARE): The Effect of Pravastatin on Coronary Events After Myocardial Infarction in Patients with Average Cholesterol Levels

Frank M. Sacks, Marc A. Pfeffer, Lemuel A. Moye, C. Morton Hawkins, Barry R. Davis, Jean L. Rouleau, Thomas G. Cole, and Eugene Braunwald

Lessons from the West of Scotland Coronary Prevention Study (WOSCOPS)

James Shepherd and Allan Gaw

Program on the Surgical Control of the Hyperlipidemias (POSCH) Trial: A Pivotal 25-Year Study

Henry Buchwald

The Air Force/Texas Atherosclerosis Prevention Study (AFCAPS/TexCAPS): Primary Prevention of Acute Major Coronary Events in Women and Men with Average Cholesterol

Stephen Weis, Michael Clearfield, Lt. Col. John R. Downs, and Antonio M. Gotto, Jr.

Long-Term Intervention with Pravastatin in Ischemic Disease (LIPID) Study: Clinical Implications for Cardiovascular Practice

Andrew M. Tonkin and David Hunt

Angiographic Results of Lipid-Lowering Trials: A Systematic Review and Meta-Analysis

Cheryl L. Holmes, Michael Schulzer, and G. B. John Mancini

Biochemical Correlates of Plaque Progression and Coronary Events

Melissa Ferraro-Borgida and David Waters

Lipid Therapy to Stabilize the Vulnerable Atherosclerotic Plaque: New Insights into the Prevention of Cardiovascular Events

B. Greg Brown and Xue-Qiao Zhao

Cholesterol-Lowering Trials with Carotid Ultrasonographic Outcomes

Robert P. Byington

Cholesterol Lowering Reduces Mortality: The Statins

David J. Gordon

✦ Subjects


Bioscience;Nutrition;Pharmaceutical Science;Clinical Trials - Pharmaceutical Science


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