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Cholesterol in Alzheimer's disease

✍ Scribed by Leila A Shobab; Ging-Yuek R Hsiung; Howard H Feldman


Book ID
114408181
Publisher
The Lancet
Year
2005
Tongue
English
Weight
196 KB
Volume
4
Category
Article
ISSN
1474-4465

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## Abstract Fundamental questions on the pathogenesis of Alzheimer's disease (AD) are how nontoxic, soluble amyloid β‐protein (AΞ²) is converted to its toxic, aggregated form and how functional tau is hyperphosphorylated to form neurofibrillary tangles. Growing evidence from recent biochemical and c