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Cholesterol Binding Regulates Prokaryotic Kir Channels

✍ Scribed by Singh, Dev; Shentu, Tzu-Pin; Enkvetchakul, Decha; Levitan, Irena


Book ID
122204520
Publisher
Biophysical Society
Year
2011
Tongue
English
Weight
57 KB
Volume
100
Category
Article
ISSN
0006-3495

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Cholesterol and Kir channels
✍ Irena Levitan πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 306 KB

## Abstract To date, most of the major types of Kir channels, Kir2s, Kir3s, Kir4s, and Kir6s, have been found to partition into cholesterol‐rich membrane domains and/or to be regulated by changes in the level of membrane cholesterol. Surprisingly, however, in spite of the structural similarities be