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Structural Determinants of the Regulation of Kir Channels by Cholesterol

✍ Scribed by Levitan, Irena

Book ID
122289799
Publisher
Biophysical Society
Year
2009
Tongue
English
Weight
81 KB
Volume
96
Category
Article
ISSN
0006-3495

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## Abstract Mutations in Kir2.1 inwardly rectifying potassium channels are associated with Andersen syndrome, a disease characterized by potentially fatal cardiac arrhythmias. While several Andersen‐associated mutations affect membrane expression, the cytoplasmic signals that regulate Kir2.1 traffi