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Cholestatic potentials of α-naphthylisothiocyanate (anit) and β-naphthylisothiocyanate (bnit) in the isolated perfused rat liver

✍ Scribed by David C. Kossor; Jeffrey A. Handler; Deanne M. Dulik; Paul C. Meunier; Thomas B. Leonard; Robin S. Goldstein


Book ID
115783623
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
520 KB
Volume
46
Category
Article
ISSN
0006-2952

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The protective effect of melatonin, 6-hydroxymelatonin and N-acetylserotonin against alpha-naphthylisothiocyanate (ANIT)-induced liver injury was investigated and compared in rats injected once with the hepatotoxicant (75 mg/kg body weight). In rats injected with ANIT alone, liver injury with choles