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Cholestasis induced by lithocholate and its glucuronide: their biliary excretion and metabolism

✍ Scribed by Hajime Takikawa; Hideaki Ohki; Naoyo Sano; Takeshi Kasama; Masami Yamanaka


Book ID
115740776
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
364 KB
Volume
1081
Category
Article
ISSN
0005-2760

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Pharmacologic doses of ethinylestradiol are known to cause intrahepatic cholestasis in the rat. This is associated with a decrease in liver plasma membranes fluidity and a modification of the activity of membrane-bound enzymes related to bile flow. The intake of a diet containing highly polyunsatura