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Choleretic and cholestatic effects of infused bile salts in the rat

โœ Scribed by R. Drew; B. G. Priestly


Book ID
112661249
Publisher
Springer
Year
1979
Tongue
English
Weight
354 KB
Volume
35
Category
Article
ISSN
1420-682X

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Valproic acid (WA) is an anticonvulsant agent which produced marked choleresis in the rat. Bile flow rate increased from 50 to 60 pl per min per kg to 120 to 145 p1 per min per kg immediately after i.v. injection of VPA (37.5 to 150 mg per kg; 2 ml per kg) in male Sprague-Dawley rats. The duration o