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Cholecystokinin modulates both the development and the expression of behavioral sensitization to amphetamine in the rat

โœ Scribed by G. R. Wunderlich; N. J. DeSousa; F. J. Vaccarino


Publisher
Springer
Year
2000
Tongue
English
Weight
85 KB
Volume
151
Category
Article
ISSN
0033-3158

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โœ William A. Carlezon Jr.; Kurt Rasmussen; Eric J. Nestler ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 68 KB

Morphine (3.0 mg/kg, SC) stimulates locomotor activity in rats, and this effect sensitizes with repeated intermittent treatment. We examined the ability of the AMPA antagonist LY293558, administered systemically over a range of doses (0.1-3.0 mg/kg), to alter morphine sensitization. Pretreatment wit