Ontogeny of the enhanced behavioral response to amphetamine in amphetamine-pretreated rats
โ Scribed by M. G. Kolta; F. M. Scalzo; S. F. Ali; R. R. Holson
- Publisher
- Springer
- Year
- 1990
- Tongue
- English
- Weight
- 775 KB
- Volume
- 100
- Category
- Article
- ISSN
- 0033-3158
No coin nor oath required. For personal study only.
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The ambulatory and rearing responses to d-amphetamine were studied in a battery of recombinant inbred strains and in three closely related strains: C57BL/6J, C57Bl/10J, and C57BL/LBy. Differences in the increase of ambulation (stimulation) caused by d-amphetamine were seen between C57BL/6By and the
In the present experiments, the effects of a wide range of doses of d-amphetamine and apomorphine were studied on investigatory behavior in an automated eight-hole box. Amphetamine (0.125, 0.25, 0.5, 1.0, 3.0, 5.0 mg/kg) increased frequency and total duration of responses, and decreased mean duratio