𝔖 Bobbio Scriptorium
✦   LIBER   ✦

CHO cells in biotechnology for production of recombinant proteins: current state and further potential

✍ Scribed by Jee Yon Kim; Yeon-Gu Kim; Gyun Min Lee

Publisher
Springer
Year
2011
Tongue
English
Weight
427 KB
Volume
93
Category
Article
ISSN
1432-0614

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Regulation of XBP-1 signaling during tra
Regulation of XBP-1 signaling during transient and stable recombinant protein production in CHO cells
✍ Sebastian C. Y. Ku; Poh Choo Toh; Yih Yean Lee; Janet Chusainow; Miranda G. S. Y πŸ“‚ Article πŸ“… 2009 πŸ› American Institute of Chemical Engineers 🌐 English βš– 885 KB

## Abstract X‐box binding protein 1 (XBP‐1) is a key regulator of cellular unfolded protein response (UPR). The spliced isoform of XBP‐1, XBP‐1S, is a transcription activator, which is expressed only when UPR is induced. However, the impact of recombinant protein production on the regulation of XBP

Bioreactor strategies for improving prod
Bioreactor strategies for improving production yield and functionality of a recombinant human protein in transgenic tobacco cell cultures
✍ Ting-Kuo Huang; Michael A. Plesha; Bryce W. Falk; Abhaya M. Dandekar; Karen A. M πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 289 KB πŸ‘ 1 views

## Abstract Plant cell culture production of recombinant products offers a number of advantages over traditional eukaryotic expression systems, particularly if the product can be targeted to and purified from the cell culture broth. However, one of the main obstacles is product degradation by prote

Combined approach of NMR and chemometric
Combined approach of NMR and chemometrics for screening peptones used in the cell culture medium for the production of a recombinant therapeutic protein
✍ Ying Luo; Guoxiang Chen πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 197 KB πŸ‘ 2 views

## Abstract Soy peptones or soy hydrolysates are widely used as key medium additives in serum‐free cell culture processes for industrial production of therapeutic recombinant proteins. The heterogeneous nature of these vegetable‐derived materials can lead to substantial lot‐ to‐lot variability in c