A procedure was standardized for extracting chloropromazine and its sulfoxide from the blood and for applying a recently developed fluorometric assay method to determine blood levels of these two compounds in schizophrenic patients receiving chlorpromazine therapy. The described methodology opens av
โฆ LIBER โฆ
Chlorpromazine metabolism VII: New quantitative fluorometric determination of chlorpromazine and its sulfoxide
โ Scribed by Pushkar N. Kaul; Lloyd R. Whitfield; Mervin L. Clark
- Book ID
- 102914285
- Publisher
- John Wiley and Sons
- Year
- 1976
- Tongue
- English
- Weight
- 691 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
โฆ Synopsis
Combining Eqs. A2 and A3 and intematinp: with these boundary For h d >> 1, h. A10 can be reduced to: -conditions give: C f -D " C m + (cf.+=)(l-;) Df Df for (0 5 x 5 h). dr2 D m ( D f : ) Substituting Eq. A4 into Eq. A3 and rearranging give: d*C,-k/ D,+-c,= Equation Ad can be solved analytically for C, to give: (%to + DmCmo) (1 -; ) Dm + Df/K where:
(Eq. A4)
(Eq. All)
'
๐ SIMILAR VOLUMES
Chlorpromazine metabolism VIII: Blood le
โ
Pushkar N. Kaul; Lloyd R. Whitfield; Mervin L. Clark
๐
Article
๐
1976
๐
John Wiley and Sons
๐
English
โ 459 KB