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Chloro(trimethyl)silane-catalyzed three-component condensation of diethyl 3,3′-(1,3-phenylene)bis(3-oxo-propanoate) with aromatic aldehyde and urea. New synthesis of diethyl 4,4′-(1,3-phenylene)bis(2-oxo-1,2,3,6-tetrahydropyrimidine-5-carboxylates)

✍ Scribed by S. V. Vdovina; L. V. Mustakimova; V. A. Mamedov


Book ID
111464667
Publisher
SP MAIK Nauka/Interperiodica
Year
2008
Tongue
English
Weight
167 KB
Volume
44
Category
Article
ISSN
1070-4280

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Biginelli-like three component reaction:
✍ Javad Azizian; Ali A. Mohammadi; M. Kohshari; Ali R. Karimi; Mohammad R. Mohamma 📂 Article 📅 2007 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 243 KB

## Abstract magnified image In the context of our high‐throughput organic synthesis program, we have studied the reactivity of special β‐keto esters toward the Biginelli reaction. We have found that a diethyl‐3‐oxoglutarate reacts with one molecule of urea and one molecule of aldehyde under solven