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ChemInform Abstract: One-Pot Synthesis of Diethyl 4,4′-(1,4-Phenylene)bis [6-(halomethyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylates] (IV) and Their Bispyrrolocyclization.

✍ Scribed by Iryna O. Lebedyeva; Mykhaylo V. Povstyanoy; Vyacheslav M. Povstyanoy; Oleksandr G. Panasyuk; Evgen S. Guban; Aleksey B. Ryabitskii


Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
42
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Synthesis and Excha
✍ C. A. BATTY; M. K. MANTHEY; J. KIRK; M. MANTHEY; R. I. CHRISTOPHERSON; T. HAMBLE 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB 👁 2 views

Synthesis and Exchange Reactions of 5-Alkyl-2-oxo-6-thioxo-1,2,3,6-Tetrahydropyrimidine-4-carboxylic Acids. -The title compounds are prepared as potential dihydroorotase inhibitors. H/D-exchange studies establish a high tendency towards epimerization at C-5. No epimerization is observed under physi