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Chlormadinone acetate (6-chloro-17-hydroxypregna-4,6-diene-3,20-dione acetate)

✍ Scribed by Chandross, R. J. ;Bordner, J.

Book ID
117859433
Publisher
International Union of Crystallography
Year
1975
Weight
394 KB
Volume
31
Category
Article
ISSN
0567-7408

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The synthesis of 6-chloro-17-hydroxypreg
The synthesis of 6-chloro-17-hydroxypregna-4,6-diene-3,20-dione-4βˆ’14c acetate (chlormadinone-4βˆ’14C acetate)
✍ K. H. Palmer; R. W. Handy; M. E. Wall πŸ“‚ Article πŸ“… 1971 πŸ› John Wiley and Sons 🌐 French βš– 329 KB

Chlormadinone-4-14C acetate ( V ) was synthesized from 17%hydroxyprogesterone-4-14C ( I ) by dehydrogenation to the 4,6-diene ( I I ) which was converted to the 6-chloro-4,6-diene ( I V ) via the intermediate 6a,7aor-epoxy compound ( I I I ) , Acetylation of ( I V ) gave chIormadinone-4-14C acetate