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Chitosan/VEGF-sIRNA nanoparticle for gene silencing

✍ Scribed by Yan Yang; Xiudong Liu; Demeng Zhang; Weiting Yu; Guojun lv; Hongguo Xie; Jiani Zheng; Xiaojun Ma


Book ID
113694775
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
567 KB
Volume
152
Category
Article
ISSN
0168-3659

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We have previously introduced the use of the biomaterial chitosan to form chitosan/siRNA nanoparticles for gene silencing protocols. This present study shows that the physicochemical properties (size, zeta potential, morphology and complex stability) and in vitro gene silencing of chitosan/siRNA nan