Chitosan derivatives as HIV-1 inhibitors
β Scribed by Artan, Murat; Karadeniz, Fatih; Kim, Moon-Moo; Kim, Se-Kwon
- Book ID
- 122568862
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 56 KB
- Volume
- 136
- Category
- Article
- ISSN
- 0168-1656
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π SIMILAR VOLUMES
A series of HIV-1 protease inhibitors containing an epsilon substituted lysinol backbone was synthesized. Two novel synthetic routes using N-boc-L-glutamic acid alpha-benzyl ester and 2,6-diaminopimelic acid were developed. Incorporation of this epsilon substituent enabled access to the S2 pocket of
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