## Abstract Chitosan/tripolyphosphate (CHIT/TPP) and chitosan/tripolyphosphate/chondroitin sulfate (CHIT/TPP/CHS) core‐shell type microspheres were prepared by polyelectrolyte complexation in order to develop a biocompatible matrix for drug delivery. The continual method using a multi‐loop reactor
✦ LIBER ✦
Chitosan Based Hydrogel Microspheres as Drug Carriers
✍ Scribed by Lucia Vodná; Silvia Bubeníková; Dušan Bakoš
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 57 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1616-5187
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## Abstract To simulate extra‐cellular matrix, a novel three‐dimensional scaffold of polyelectrolyte complex (PEC) hydrogel as an osteoblast carrier was synthesized. First, chitosan, a natural glycosaminoglycan, was modified by phosphorylation to obtain a water‐soluble phosphorylated chitosan (__P_