Chitosan and its derivatives for gene delivery
β Scribed by Kuen Yong Lee
- Publisher
- The Polymer Society of Korea
- Year
- 2007
- Tongue
- English
- Weight
- 967 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1598-5032
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## Abstract The covalent functionalization of graphene oxide (GO) with chitosan (CS) is successfully accomplished via a facile amidation process. The CSβgrafted GO (GOβCS) sheets consist of about 64 wt.% CS, which imparts them with a good aqueous solubility and biocompatibility. Additionally, the p
Encapsulation of DNA (varying type and molecular weight) in vesicles (dehydration-rehydration vesicles; DRV) prepared from zwitterionic phospholipids using the dehydration-rehydration method was determined to be in the range of 10-90%. Encapsulation was dependent on the amount of DNA added but not i