CHIRBASE, a graphical molecular database on the separation of enantiomers by liquid-, supercritical fluid-, and gas chromatography
β Scribed by Bernhard Koppenhoefer; Andreas Nothdurft; Joanna Pierrot-Sanders; Patrick Piras; Cristina Popescu; Christian Roussel; Matthias Stiebler; Ulrich Trettin
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 595 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0899-0042
No coin nor oath required. For personal study only.
β¦ Synopsis
In order to cope with the increasing number of publications on the separation of enantiomers by chromatography on a chiral stationary phase, the graphical molecular database CHIRBASE was created. In the present state, the database package covers information (structural, bibliographic, and chromatographic data) on liquid-, supercritical fluid-, and gas chromatography; other methods will follow. CHIRBASE, running on the MDL software Chembasee, meets the requirements of contemporary information management in the chemical and pharmaceutical industry. (Detailed information including a demo-version of each part of CHIRBASE can be obtained from the authors on request.
π SIMILAR VOLUMES
Enantiomeric separation of a variety of drugs and related compounds was achieved on an (S)-naphthylethylcarbamoylated-p-cyclodextrin (SNEC-CD) chiral stationary phase (CSP) using sub-and supercritical fluid chromatography (SFC). Compounds previously resolved on native or derivatized cyclodextrin CSP
The four optical isomers of a new calcium channel blocker LF 2.0254 (developed by Laboratoires Fournier) are resolved by chromatography using chiral stationary phases. Two methods are proposed: the first one involving two chiral stationary phases ## Methods Apparatus LC was performed with a modul