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Chirality directed self-assembly. Resolution of 2,5-diazabicyclo[2.2.2]octane-3,6-dione and crystal structures of its racemic and (−) enantiomeric forms

✍ Scribed by Marie-Josèphe Brienne; Jacqueline Gabard; Martine Leclercq; Jean-Marie Lehn; Michèle Cesario; Claudine Pascard; Michel Chevé; Gilles Dutruc-Rosset


Publisher
Elsevier Science
Year
1994
Tongue
French
Weight
321 KB
Volume
35
Category
Article
ISSN
0040-4039

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Synthesis and Crystal Structure of 3,3,6
✍ Nasser Mawad; Fatemeh Ghorbani-Salman Pour; Anthony Linden; Heinz Heimgartner 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 German ⚖ 360 KB

The synthesis of 3,3-dimethylmorpholine-2,5-diones 4a was achieved conveniently via the direct amide cyclization of the linear precursors of type 3, which were prepared by coupling of 2,2-dimethyl-2H-azirin-3-amines 2 with 2-hydroxyalkanoic acids 1. Thionation of 4a with Lawessons reagent yielded th