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Chiral Zinc Amides as the Catalysts for the Enantioselective Addition of Diethylzinc to Aldehydes †

✍ Scribed by Prasad, K. R. K.; Joshi, N. N.


Book ID
120712053
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
92 KB
Volume
62
Category
Article
ISSN
0022-3263

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Optically active amino thioacetate derivatives of (+l-norephedrine were found to act as effective catalysts for enantioselective addition of diethylzinc to aldehydes. This reaction provided optically active secondary alcohols with e.e. of up to >99%.