The application of achiral/chiral couple
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Irving W. Wainer
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Article
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1989
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Elsevier Science
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English
⚖ 390 KB
The use of achiral/chiral coupled-column HPLC in the direct analysis of the enantiomers of chiral drugs in biological samples is reviewed. The method has been applied to a study of the pharmacokinetics of (+)- and (-)-terbutaline, the resolution of the stereoisomers of leucovorin and the determinati