Chiral recognition of ethers by NMR spectroscopy
✍ Scribed by Helmut Duddeck; Edison Díaz Gómez
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 295 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0899-0042
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📜 SIMILAR VOLUMES
tinued for 36 h. The clear bright yellow solution was filtered, and, after removal of solvent, the residue (2) was recrystallized from SO2; yield 2.3 g (86%,).
It was found that the oxirane ring is a functional group amenable to chiral discrimination by dirhodium-MTPA complexes. Considerable signal shifts up to 0.7 ppm are observed for 1 H nuclei close to the rhodium atoms in the complex. In analogy to previously reported olefins, this method appears to be
The 1H NMR spectra of a variety of chiral racemic nitriles were recorded in in the absence CDCl 3 and presence of dirhodium tetra-(R)-a-methoxy-a-(triÑuoromethyl)phenylacetate MTPA 4 MosherÏs [Rh 2 (MTPA) 4 ; acid]. Moderate 1H signal shifts but clear diastereomeric dispersions due to complexation w