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Chiral Phosphino- and (Phosphinooxy)-Substituted N-Heterocyclic Carbene Ligands and Their Application in Iridium-Catalyzed Asymmetric Hydrogenation

✍ Scribed by Steve Nanchen; Andreas Pfaltz

Book ID
102253439
Publisher
John Wiley and Sons
Year
2006
Tongue
German
Weight
202 KB
Volume
89
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

Enantiomerically pure iridium complexes with phosphino‐ and (phosphinooxy)‐substituted N‐heterocyclic carbene (NHC) ligands were synthesized. Investigation of their electronic properties showed a similar trans influence of the phosphino (or phosphinooxy) and the NHC units. The complexes were tested in iridium‐catalyzed hydrogenation. While low conversions were observed with unfunctionalized olefins, the catalysts proved to be suitable for hydrogenation of the α,β‐unsaturated ester 20, allylic alcohol 21, and imine 22. The enantioselectivities were, however, moderate.

📜 SIMILAR VOLUMES

Chiral Phosphino- and (Phosphinooxy)-Sub
Chiral Phosphino- and (Phosphinooxy)-Substituted N-Heterocyclic Carbene Ligands and Their Application in Iridium-Catalyzed Asymmetric Hydrogenation.
✍ Steve Nanchen; Andreas Pfaltz 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 21 KB 👁 1 views

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