Preparation of chiral annulated indenes
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Ronald L. Halterman; Lisa D. Crow
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Article
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2003
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Elsevier Science
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French
⚖ 148 KB
A three-step procedure for the synthesis of chiral annulated indenes is described in which nopinone, verbenone and menthone are converted to their enolate form, alkylated with 2-bromomethylbromobenzene, ring-closed with CrCl 2 /cat. NiCl 2 and dehydrated with catalytic acid.