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Resolution of 1,3-alkanediols via chiral spiroketals derived from ℓ-menthone

✍ Scribed by Toshiro Harada; Hideaki Kurokawa; Akira Oku


Book ID
108383087
Publisher
Elsevier Science
Year
1987
Tongue
French
Weight
224 KB
Volume
28
Category
Article
ISSN
0040-4039

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Preparation of chiral annulated indenes
✍ Ronald L. Halterman; Lisa D. Crow 📂 Article 📅 2003 🏛 Elsevier Science 🌐 French ⚖ 148 KB

A three-step procedure for the synthesis of chiral annulated indenes is described in which nopinone, verbenone and menthone are converted to their enolate form, alkylated with 2-bromomethylbromobenzene, ring-closed with CrCl 2 /cat. NiCl 2 and dehydrated with catalytic acid.