Chiral N-phosphonyl imines attached by 1-naphthyl group were found to react with lithium malonate enolates smoothly to give chiral b-aminomalonates. Good yields and excellent diastereoselectivity were achieved for sixteen examples. The chiral auxiliary can be readily removed by treating with trifluo
✦ LIBER ✦
Chiral N-Phosphonyl Imine Chemistry: Asymmetric Additions of Ester Enolates for the Synthesis of β-Amino Acids
✍ Scribed by Jianlin Han; Teng Ai; Thao Nguyen; Guigen Li
- Book ID
- 111368564
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 144 KB
- Volume
- 72
- Category
- Article
- ISSN
- 1747-0277
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