Chiral ligands containing heteroatoms:13. Optically active 4-(2′-pyridyl)-1,3-oxazolidines: An improved synthesis of 2-(2′-pyridyl)-2-aminoalcohols
✍ Scribed by Sandra Conti; Sergio Cossu; Giampaolo Giacomelli; Massimo Falorni
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- French
- Weight
- 579 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0040-4020
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Treatment of (-)-O-acyllactamides or mandelamides with TBSOTf in the presence of base gives optically active 2-oxy-1,3-oxazolidin-4-ones stereoselectively, which serve as useful precursors for the preparation of optically active secondary 2-pyrrolidones via radical cyclization and subsequent one-ste
Three new metal -organic supramolecular complexes based on the linking unit 2,5-bis(4-pyridyl)-1,3,4-oxadiazole (L) and inorganic Mn II , Fe II , Ag I salts have been prepared and structurally determined by single-crystal X-ray analysis. Using L to react with Mn(ClO 4 ) 2 , in which the hydrogen bo
## Abstract An efficient enantioselective synthesis of 3‐acetoxy __trans__‐__β__‐lactams **7a** and **7b** __via__ [2+2] cycloaddition reactions of imines **4a** and **4b**, derived from a polycyclic aromatic amine and bicyclic chiral acid obtained from (+)‐car‐3‐ene, is described. The cycloadditio