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Chiral Lewis Acid Controlled Synthesis (CLAC Synthesis): Chiral Lewis Acids Influence the Reaction Course in Asymmetric Aldol Reactions for the Synthesis of Enantiomeric Dihydroxythioester Derivatives in the Presence of Chiral Diamines Derived from L-Proline

✍ Scribed by Prof. Dr. Shū Kobayashi; Mineko Horibe


Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
997 KB
Volume
3
Category
Article
ISSN
0947-6539

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Synthesis of Chiral 1,3-Diamines Derived
✍ Dr. Koichi Kodama; Kazuyuki Sugawara; Prof. Takuji Hirose 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 438 KB 👁 1 views

## Abstract In this study, 13 different chiral 1,3‐diamines were synthesized from (−)‐__cis__‐2‐benzamidocyclohexanecarboxylic acid. They were successfully applied as ligands in the Cu‐catalyzed asymmetric Henry reaction between benzaldehyde and nitromethane. It was confirmed that the enantioselect