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Chiral cynthesis of D- and L-3,3-diphenylalanine (DIP), unusual α-amino acids for peptides of biological interest

✍ Scribed by Huai G. Chen; V.G. Beylin; M. Marlatt; B. Leja; O.P. Goel

Book ID: 104225070
Publisher: Elsevier Science
Year: 1992
Tongue: French
Weight: 253 KB
Volume: 33
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)92070-7

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✦ Synopsis

The asymmetric syntheses of D-(R)-(-)-and L-(S)-(+)-3,3diphenylahmine (Dip) are described

Currently, there is great interest in the design and synthesis of unusual a-amino acids which may provide specific conformational restraint, and also biostability to degradation by peptidases to small peptides/peptidomhnetics

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