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Chiral Binaphthyl-Derived Amine-Thiourea Organocatalyst-Promoted Asymmetric Morita—Baylis—Hillman Reaction.

✍ Scribed by Jian Wang; Hao Li; Xinhong Yu; Liansuo Zu; Wei Wang


Publisher
John Wiley and Sons
Year
2006
Weight
21 KB
Volume
37
Category
Article
ISSN
0931-7597

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✍ Yong-Ling Shi; Min Shi 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 153 KB 👁 2 views

## Abstract A new kind of bifunctional (thio)urea‐phosphine catalyst was synthesized and applied to the aza‐Morita–Baylis–Hillman reaction of __N__‐sulfonated imines with methyl vinyl ketone, phenyl vinyl ketone, ethyl vinyl ketone or acrolein. Moderate to excellent __ee__ and yields of the product