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Chiral 1,3,6-Trisubstituted 2,4-Dioxohexahydropyrimidines: A Convenient Stereoselective Synthesis from Aspartic Acid Derivatives.

✍ Scribed by Rosario Patino-Molina; Ivan Cubero-Lajo; M. Jesus Perez de Vega; M. Teresa Garcia-Lopez; Rosario Gonzalez-Muniz


Publisher
John Wiley and Sons
Year
2007
Weight
21 KB
Volume
38
Category
Article
ISSN
0931-7597

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A convenient synthesis of 2-amino-4H-1,3
✍ Ho Sik Kim; Tong Eun Kim; Seong Uk Lee; Dong Il Kim; Sung Wook Han; Yoshihisa Ok 📂 Article 📅 1998 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 380 KB

## Abstract The reaction of 6‐chloro‐2‐(1‐methylhydrazino)quinoxaline 4‐oxide 5 with a 2‐fold molar amount of ethyl chloroglyoxalate gave ethyl 8‐chloro‐4‐methyl‐4__H__‐1,3,4‐oxadiazino[5,6‐__b__]quinoxaline‐2‐carboxylate 6, whose reaction with hydrazine hydrate afforded the C~2~‐hydrazinocarbonyl