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Chfr is required for tumor suppression and Aurora A regulation

✍ Scribed by Yu, Xiaochun; Minter-Dykhouse, Katherine; Malureanu, Liviu; Zhao, Wei-Meng; Zhang, Dongwei; Merkle, Carolin J; Ward, Irene M; Saya, Hideyuki; Fang, Guowei; van Deursen, Jan


Book ID
109919139
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
412 KB
Volume
37
Category
Article
ISSN
1061-4036

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Phosphorylation of Akt/PKB is required f
✍ Nanami Itoh; Shuho Semba; Masafumi Ito; Hiroaki Takeda; Sumio Kawata; Mitsunori πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 683 KB

## Abstract ## BACKGROUND Akt/protein kinase B (PKB), which is included in phosphatidyl inositol‐3‐OH kinase (PI3K) signaling, controls many intracellular processes, such as the suppression of apoptosis and the promotion of the cell cycle. Therefore, the authors investigated phosphorylated Akt (Se