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Chemotherapy-related hemolytic-uremic syndrome after the treatment of head and neck cancer. A case report

✍ Scribed by William J. Gradishar; Everett E. Vokes; Kai Ni; William R. Panje

Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
626 KB
Volume
66
Category
Article
ISSN
0008-543X

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✦ Synopsis

A 62-year-old woman who was being treated for squamous cell carcinoma of the head and neck developed a chemotherapy-related hemolytic-uremic syndrome during the second cycle of neoadjuvant chemotherapy consisting of cisplatin, bleomycin, and methotrexate. Though the syndrome was suspected early, attempts at reversing the hematologic and renal abnormalities were unsuccessful. At postmortem examination, the characteristic microvascular lesions of the hemolyticuremic syndrome were found in the kidneys.

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