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Chemotherapy in low-grade astrocytoma management

✍ Scribed by M. A. Castello; A. Schiavetti; G. Varrasso; A. Clerico; C. Cappelli


Publisher
Springer
Year
1998
Tongue
English
Weight
46 KB
Volume
14
Category
Article
ISSN
0256-7040

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Six children with grade I1 astrocytomas were treated with combination chemotherapy consisting of 1,3 bis(2-chloroethyl) 1-nitrosourea (BCNU), Vincristine (VCR), intrathecal Methotrexate ( i t . MTX), and Dexamethasone. Of the children, 3 showed a partial remission, and 1 other showed clinical improv

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## Abstract ## Background Cytogenetic analysis in certain tumors is a vital part of classification and assignment of prognosis. Few studies have examined the value of cytogenetic analysis in pediatric brain tumors. This is especially true of low‐grade astrocytomas (LGA) of childhood. This study ex