Chemotherapy for malignant brain tumors of astrocytic and oligodendroglial lineage
โ Scribed by Silvia Hofer; Richard Herrmann
- Publisher
- Springer-Verlag
- Year
- 2001
- Tongue
- English
- Weight
- 82 KB
- Volume
- 127
- Category
- Article
- ISSN
- 1432-1335
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Twenty-nine patients with grade 111 or IV astrocytomas were treated with 1,3 bis(2-chloroethyl)-l-nitrosourea (BCNU), 75-100 mg/M2 intravenously (IV) for two consecutive days every four t o six weeks, in an effort to improve the quality and length of their survival following surgical resection. Twen
## Abstract ## BACKGROUND. Highโdose chemotherapy (HDCT) with autologous stem cell rescue (ASCR) has been reported to be effective in treating children with recurrent central nervous system (CNS) malignancies. ## METHODS. To evaluate the efficacy and toxicities of HDCT and ASCR, the medical reco