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Chemotherapy-associated Raynaud's phenomenon in a two-year-old girl

✍ Scribed by McGuire, Warren A. ;Passo, Murray H. ;Weetman, Robert M.

Publisher: John Wiley and Sons
Year: 1985
Tongue: English
Weight: 267 KB
Volume: 13
Category: Article
ISSN: 0098-1532
DOI: 10.1002/mpo.2950130619

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✦ Synopsis

Raynaud's phenomenon occurred in a 2year-old girl 17 months after starting multiagent chemotherapy for an endodermal sinus tumor of the vagina. Symptoms began 2 months after receiving her final dose of bleornycin, and gradually resolved over a 6-month period despite continuing vinblastine. Chernotherapy-associated Raynaud's phenome-non appears to be unusual in young children, although mild episodes of vasospasm may not be reported by children or their parents. Specific questions regarding symptoms of Raynaud's phenomenon should be asked of all children receiving vinblastine and bleomycin therapy.

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